精神分裂症患者的稳态视觉诱发电位异常

精神分裂症患者的稳态视觉诱发电位异常

KrishnanG.P.;Vohs J.L.;HetrickW.P.;B. F.O’Donnell;高中宝

【期刊名称】《世界核心医学期刊文摘：神经病学分册》

【年(卷),期】2005(000)008

【摘 要】Objective: The steady state visual evoked potential (SSVEP)can be

ud to test the frequency respon function of neural circuits. Previous

studies have shown reduced SSVEPs to alpha and lower frequencies of

stimulation in schizophrenia. We investigated SSVEPs in schizophrenia at

frequencies spanning the theta (4 Hz) to gamma (40 Hz) range. Methods:

The SSVEPs to ven different frequencies of s timulation (4, 8,17, 20, 23,

30 and 40 Hz) were obtained from 18 schizophrenia s ubjects and 33

healthy control subjects. Power at stimulating frequency (signal power)

and power at frequencies above and below the stimulating frequency

(noi power) were ud to quantify the SSVEP respons. Results: Both

groups showed a n inver relationship between power and frequency of

stimulation. Schizophrenia subjects showed reduced signal power

compared to healthy control subjects at hi gher frequencies(above 17 Hz),

but not at 4 and 8 Hz at occipital p ower was higher in

schizophrenia subjects at frequencies between 4 and 20 Hz ove r occipital

region and at 4,17 and 20 Hz over frontal region. Conclusions: SSVEP

signal power at beta and gamma frequencies of stimulation were reduced

in schiz phrenia subjects showed higher levels of EEG noi

during photic stimulation at beta and lower icance:

Inability to generate or maintain oscillations in neural networks may

contribute to deficits in visual p rocessing in schizophrenia.

【总页数】1页(P27-27)

【作 者】KrishnanG.P.;Vohs J.L.;HetrickW.P.;B. F.O’Donnell;高中宝

【作者单位】Department of Psychology Indiana University 1101 E 10th

Street Bloomington IN 47405 United States

【正文语种】中 文

【中图分类】R749.3

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