上海口译培训班专利名称:Computer implemented system for protein什么是一般过去时
and drug target design utilizing quantified
stability and flexibility relationships to
control function
发明人:Donald J Jacobs,Dennis R. Livesay
日语2级报名
申请号:US12344512
申请日:20081227
公开号:US08374828B1
公开日:
mpiayer>thailand是什么意思
20130212
专利内容由知识产权出版社提供浸的意思
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摘要:The computerized method, software, and product of this invention implements
a process for computationally designing proteins and/or associated molecular targets with desired quantitative stability/flexibility relationships (QSFR). QSFR is an innovative, high dimensional metric calculated using an improved Distance Constraint Model (DCM). This invention includes three distinct aspects: (i.) utilizing QSFR in computational molecular design of protein quences, or variations of molecular structures, to have specific stability and flexibility relationships deemed important for biochemical function for specified thermodynamic and solvent conditions; (ii.) utilizing QSFR to optimize thermodynamic and/or solvent conditions necessary for a specified molecular system to exhibit protein function characteristics, such as improved catalytic efficiency; and (iii.) utilizing QSFR to computationally screen or design small molecules and/or design its putative receptor so as to exhibit a desired affect on protein function.
申请人:Donald J Jacobs,Dennis R. Livesay
地址:Charlotte NC US,Charlotte NC US
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国籍:US,US歌曲我心飞翔
撒切尔夫人逝世代理机构:Summa, Additon & Ashe, P.A.
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