1英文单词翻译
Primary non-Hodgkin's lymphoma of the uterine cervix:
A ca report
Milica ®ivaljeviæ, Tamara Vujkov, Darjana Jovanoviæ, Aljo¹a Mandiæ, Olgica Mihajloviæ,
Mladen Prvuloviæ, Bratislav Stojiljkoviæ
ABSTRACT
Primary uterine cervical non-Hodgkin's lymphomas (NHL) are rare. Limited experience dictates careful pretherapy evaluation and multidisciplinary approach in treatment planning. A 53-year-old woman pre-nted with postmenopausal bleeding and PAP smear IIIb. Cervical biopsy and endocervical curettage biopsy revealed NHL of the uterine cervix. Abdominal hysterectomy with bilateral adnexectomy was fol-lowed by pelvic lymphadenectomy due to lymph node metastasis, 21 months after the primary opera-tion. Subquently, the patient received postoperative chemotherapy. Seven years after the ont of NHL she is alive with no evidence of dia recurrence.
KEY WORDS: Cervix Neoplasms; Lymphoma, Non-Hodgkin
Institute of Oncology Sremska Kamenica, Institutski put 4,21204 Sremska Kamenica, Serbia & Monetengero;Address correspondence to: Dr Milica ®ivaljeviæ, Institute of Oncology Sremska Kamenica, Institutski put 4, 21204Sremska Kamenica, Serbia & Monetengero; E-mail:*****************,Themanuscriptwasreceived:26.06.2004, Provisionally accepted: 05.07.2004, Accepted for publication: 19.07.2004
©2004, Institute of Oncology Sremska Kamenica, Serbia &Montenegro
CASE REPORT
dynamically
UDC: 618.126-006:616-006.44:616-089.8:615-085
the cervix. After consulting a medical oncologist, no further therapy was planned.
The patient was put on clo follow-up every 3 months. She was doing well for 21 months after the operation, when gynecological examination revealed right iliac node enlargement and abdominal ultr
asound showed hydronephrosis of the right kidney. MRI of the pelvis Figure1.Low-grade B cell non-HodgkinÕs lymphoma, invaded stroma of the uterine cervix under the normal squamocellular epithelium of the exocervix
Seven years after the first operation the patient is doing well, without evidence of dia recurrence.
英语培训机构怎么选DISCUSSION
Malignant NHLs of the uterine cervix are so rare, that less than 100 cas are described in the literature, with the largest data coming from 38 cas from English literature (2). Our patient prented with slight postmenopausal bleeding and abnormal PAP smear. According to the majority of authors, abnormal vaginal bleeding (54%), vaginal mass (12%) and dyspareunia (5%) are the most common clinical features (8). Abnormal cervical smear is only rarely found (9). The pathogenesis of cervical NHL is unclear and they are usually classified in the MALT-oma category (mucosa-associated lymphoiod tissue) becau of relatively low malignancy, good prognosis and localized growth (2,5). Individual approach should be ud in treatment decision. There are no internationally accepted recommenda-tions, due to lack of experience becau of the rarity of this condition. Stroh et al., in ana-lyzing 16 cas, recommend combination of chemotherapy and irradiation (6). Chine authors prefer combination of surgery and chemotherapy (9). Holweg et al. recommend radiation after surgical staging (10). According to our modest experience, hysterectomy with pelvic lymphadenectomy is the first step in therapy. Lymph node status dictates fur-ther chemot
消遣什么意思
herapy and/or radiotherapy.
CONCLUSION
上海全日制自考大学kabbalahMalignant NHL of the uterine cervix is a rare entity and it should be treated and followed-up by a multidisciplinary team. As a systemic dia, interdisciplinary intervention, including radical surgery, systemic chemotherapy and radiation therapy should be considered.
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Figure 2.MR tomography of pelvis. Axial ction in T1w quence before and after the application of paramagnetic contrast medium. At the level of cervix and involving fornix and ishmus, paramedianly left, an ovoid formation dia. 2 cm slightly hyperten in T1w quence (A), moderate post contrast signal intensity (B)topsage
Figure 3.Sagittal ctin in T1w quence. Tumor formation is relatively homogenous and well defined in relation to postcervical mass. No enlarged lymph nodes are obrved