初中一年级英语单词LncRNA KCNQ1OT1 (potassium voltage-gated channel subfamily Q member 1 opposite strand/antin transcript 1) aggravates acute kidney injury by activating p38/NF-κB pathway via miR-212-3p/MAPK1 (mitogen-activated protein
英语作业本八下答案kina 1) axis in psis
期刊名称： Bioengineered
作者： Changhua Liu,Bo Gao,Xiaolan Xu,Gang Zhou,Haixia Wang,Hongbin Mou 作者机构： Department of Nephrology, Subei Peoples Hospital of Jiangsu
Province, Yangzhou, China,Department of Critical Care Medicine, Subei Peoples Hospital of Jiangsu Province, Yangzhou, China
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年份： 2021年
期号： 第2期
工程技术资料关键词： Acute kidney injury;MAPK1;KCNQ1OT;p38/nf-κB;ceRNApicco
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英文地址怎么写>高中军训心得体会没问题英语怎么说摘要：Acute kidney injury (AKI), a common complication of psis, is characterized by a rapid loss of renal excretory function. A variety of etiologies and pathophysiological process may contribute to AKI. Previously, mitogen-activated protein kina 1 (MAPK1) was reported to regulate cellular process in various psis-associated dias. The current study aimed to further explore the biological function and regulatory mechanism of MAPK1 in psis-induced AKI. In our study, MAPK1 exhibited high expression in the rum of AKI patients. Functionally, knockdown of MAPK1 suppresd inflammatory respon, cell apoptosis in respon of lipopolysaccharide (LPS) induction in HK-2 cells. Moreover, MAPK1 deficiency alleviated renal inflammation, renal dysfunction, and renal injury in vivo . Mechanistically, MAPK1 could activate
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