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Formation of nuclear heterochromatin 期刊名称： Epigenetics
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作者： Guetg, Claudio,Santoro, Raffaella伯瑞英语>人教五年级英语
年份： 2012年comprehensive
information是什么意思期号： 第8期最贵伏特加被盗
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关键词： PARP1;TIP5;heterochromatin;nucleolus;nucleus;pRNA;pericentric
heterochromatin;rDNA
摘要：Establishment and inheritance of heterochromatic states is critical in maintaining genome integrity and gene expression state. The elucidation of the mechanisms implicated in the process is fundamental to understand the control of epigenetic regulation of the genome. Recently, the nucleolus emerged as an important component of the nuclear architecture. Although the nucleolus is the most active site of cellular transcription, it is also an attractive compartment for nuclear heterochromatic regions, such as pericentric repeats, inactive X chromosome and regions with low gen
中英文e density significantly enriched in represd genes. The coexistence of euchromatic and heterochromatic rRNA genes in each cell reflects the two opposite functions of the nucleolus. An epigenetic network that is controlled by NoRC complex establishes
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