专利名称：RESISTANCE TO POLYPHENON E DUE TO INCREASED BCL-2 EXPRESSION
发明人：JOE, Andrew, K.,WEINSTEIN, I., Bernard
beamangle申请号：US2008073487
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申请日：20080818
公开号：WO09/126172P1
公开日：loadlibrary
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申请表英文
20091015
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专利内容由知识产权出版社提供
摘要：The prent invention disclos BCL2 gene and protein expression are significantly higher in cancer cells resistant to the growth inhibitory effects of Polyphenon E (Poly E), and decreasing BCL2 expression or activity would restore nsitivity to Poly E. The results indicate that BCL2 could be a marker of resistance to Poly E and could be ud to identify patients who may not benefit clinically from treatment or prevention with Poly E. Furthermore, treatment regimens that combine Poly E and BCL2 inhibitors may be effective against cancers with high BCL2 expression.
申请人：JOE, Andrew, K.,WEINSTEIN, I., Bernard
地址：US,US,US龙井茶英语
国籍：US,US,USallegation
四级照
代理机构：CHAN, Albert, Wai-Kit
生物燃料
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