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菲利普 霍夫曼专利名称：Methods for early detection of pregnancy in cows
发明人：Nagappan Mathialagan,Michael
McGrath,Robert Schenkel
申请号：US11587391
clipper
mr and mrs smith申请日：20050427
简称英文
公开号：US07604950B2
公开日：
20091020
专利内容由知识产权出版社提供
摘要：Disclod are methods for determining the pregnancy status of a cow by detecting a pregnancy-associated glycoprotein (PAG) level that compris proteins prent in an acidic protein fraction of day 55 to day 60 bovine placental tissue. The methods may involve using novel polyclonal and monoclonal antibodies that have been generated using the acidic protein fraction as an immunogen. According to the method, the cow is pregnant when the PAG level is prent at an elevated level in a sample obtained from the cow. The invention provides accurate methods of detecting pregnancy at early stages and has the benefit of allowing early post partum detection of pregnancy status with few fal positive results. The antibodies for detecting the PAG level will also be uful in combination with detecting elevated progesterone levels, thus providing an even more effective pregnancy detection method. The benefit of this early pregnancy detection is that identifying cows that are not pregnant very shortly after breeding allows for timely rebreeding and minimizes the amount of time the cow is open. Also disclod are methods for making a breeding decision for a cow. The methods allow a herd manager to make breeding decisions bad on the PAG level and optionally,
progesterone levels, detected in a biological sample taken from a cow suspected of being in the early stages of pregnancy.
vgr申请人：Nagappan Mathialagan,Michael McGrath,Robert Schenkel
地址：Ballwin MO US,Chesterfield MO US,St. Louis MO US
arpanet国籍：US,US,US
folks
代理机构：Howrey LLP
运动会开幕式致辞
代理人：Matthew L. Madn
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