图钉英文
专利名称：METHOD OF MEASURING INHERENT
investment bankingCLEARANCE, BINDING RATIO TO SERUM
PROTEIN AND ORGAN CLEARALNCE OF
DRUG
发明人：KATO, Motohiro,NABUCHI,
Yoshiaki,UCHIMURA, Takahide,TACHIBANA,
Tatsuhiko,ARAI, Shinichi
申请号：JP2001007804
b级英语考试申请日：20010907
公开号：WO02/021124P1
北上教育
公开日：
snookered
20020314
专利内容由知识产权出版社提供
灰姑娘的动画片摘要：A method of measuring the inherent clearance and the binding ratio to rum protein of a drug characterized by comprising: a first step of preparing at least three samples, the total drug concentration (Ct) of the drug, the rum protein concentration (x) and the metabolic enzyme concentration (y) of which are known, and conducting a metabolic reaction; a cond step of measuring the concentration of the drug remaining in the liquid reaction mixture obtained in the first step 1 to thereby calculate the metabolic speed (v) of the drug; and a third step of determining the inherent clearance and the binding ratio to rum protein of the drug from the above-described total
drug concentration (Ct), the above-described rum protein concentration (x), the above-described metabolic enzyme concentration (y) and the above-described metabolic speed (v) on the basis of a definite relationship among the total drug concentration (Ct), the rum protein concentration (x), the metabolic enzyme concentration (y), the metabolic
incubusspeed (v), and the inherent clearance (A), the binding ratio to rum protein (D) unbinding fraction in rum (fp) and the unbinding fraction in reaction mixture (ft) of the unbonded drug (A). According to this method, the inherent clearance, the binding ratio to rum protein and the organic clearance of a drug can be quickly measured without quantifying the drug adsorbed by a matrix.
申请人：KATO, Motohiro,NABUCHI, Yoshiaki,UCHIMURA, Takahide,TACHIBANA, Tatsuhiko,ARAI, Shinichi
地址：JP,JP,JP,JP,JP,JP
the other woman
gaga是什么意思国籍：JP,JP,JP,JP,JP,JPworked怎么读
代理机构：HASEGAWA, Yoshiki
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