专利名称：LONG-ACTING OXYNTOMODULIN
FORMULATION AND METHODS OF
PRODUCING AND ADMINISTERING SAME 发明人：HERSHKOVITZ, Oren,BAR-ILAN, Ahuva,LEV, Vered,TZUR, Yaron
泰坦尼克号英文名申请号：IL2017/050645
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申请日：20170608
公开号：WO2017/212494A1
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专利内容由知识产权出版社提供
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专利附图：
摘要：Pharmaceutical formulations and pharmaceutical compositions comprising
rever PEGylated oxyntomodulin conjugates, and methods of producing, and using the same are described. Conjugates include tho attaching a polyethylene glycol polymer (PEG polymer) and 9- fluorenylmethoxycarbonyl (Fmoc) or 2-sulfo-9-fluorenylmethoxycarbonyl (FMS) to a oxyntomodulin peptide, wherein the PEG polymer is attached to the amino terminus or to an amino residue within the oxyntomodulin via a flexible linker, wherein the flexible linker compris a Fmoc or a FMS.
申请人：OPKO BIOLOGICS LTD.
地址：16 Ashlegan St. 8211804 Kiryat Gat IL
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代理人：VAN DER BOOM, Tamar et al.
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