Multiwalled carbon nanotubes enhance human bone marrow menchymal stem cells' spreading but delay their proliferation in the direction of differentiation acceleration口若悬河
期刊名称： Cell Adhesion & Migration
作者： Deligianni,Despina D
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年份： 2014年
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期号： 第6期
关键词： cell differentiation;cell proliferation;cell spreading;human bone marrow menchymal stem cells;multiwalled carbon nanotubesbombing
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摘要：Investigating the ability of films of pristine (purified, without any functionalization) multiwalled carbon nanotubes (MWCNTs) to influence human bone marrow menchymal stem cells' (hBMSCs) proliferation, morphology, and differentiation into osteoblasts, we concluded to the following: A. MWCNTs delay the proliferation of hBMSCs but increa their differentiation. The enhancement of the 西印度群岛
differentiation markers could be a result of decread proliferation and maturation of the extracellular matrix B. Cell spread on MWCNTs toward a polygonal shape with many thin filopodia to attach to the surfaces. Spreading may be critical in supporting osteogenic differentiation in pre-osteoblastic progenitors, being related with cytoskeletal tension. C. hBMSCs prefer MWCNTs than tissue plastic to attach and grow, being non-toxic to the cells. tell me your wish
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