PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAIN

更新时间:2023-07-01 21:38:41 阅读: 评论:0

专利名称:PYRAZOLE DERIVATIVE, MEDICINAL
百灵科
缓解工作压力的方法COMPOSITION CONTAINING THE SAME,
supply的用法
MEDICINAL USE THEREOF AND
当我想起你 张学友
INTERMEDIATE IN PRODUCING THE SAME 发明人:FUJIKURA, HIDEKI,KIKUCHI,
NORIHIKO,TAZAWA, SHIGEKI,YAMATO,
TOKUHISA,ISAJI, MASAYUKI
申请号:EP03753967
申请日:20030930
公开号:EP1550668A4
nosmoking公开日:
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20081001
专利内容由知识产权出版社提供
摘要:The prent invention provides pyrazole derivatives reprented by the general formula: wherein R<1> reprents H, an optionally substituted C1-6 alkyl group etc. ; one of Q and T reprents a group lected from the following goups: , and the other reprents -(CH2)n-Ar wherein Ar reprents an optionally substituted C6-10 aryl group or an optionally substituted C1-9 heteroaryl group; and n reprents an integral number from 0 to 2, an optionally substituted C1-6 alkoxyl group, an optionally substituted amino group, an optionally substituted C2-9 heterocycloalkyl group or an optionally substituted heterocycle-fud phenyl group; R reprents an optionally substituted C3-8 c
ycloalkyl group, an optionally substituted C6-10 aryl group etc., pharmaceutically acceptable salts thereof or prodrugs thereof, which exhibit an excellent inhibitory activity in human 1,5-anhydroglucitol/fructo/manno transporter and are uful as agents for the prevention, inhibition of progression or treatment of a dia associated with the留学美国条件>judge
skiniceexcess uptake of at least a kind of carbohydrates lected from gluco, fructo and manno or a dia associated with hyperglycemia (e.g., diabetic complications, diabetes, etc.), and pharmaceutical compositions comprising the same, pharmaceutical us thereof, and intermediates for production thereof.
申请人:KISSEI PHARMACEUTICAL CO., LTD.
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