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专利名称：8-QUINOLINXANTHINE AND 8-
ISOQUINOLINXANTHINE DERIVATIVES AS
PDE 5 INHIBITORS韩语翻译网站
发明人：BHALAY, Gurdip,COLLINGWOOD, Stephen Paul,FAIRHURST, Robin Alec,GOMEZ, Sylvie,
Felicite,NAEF, Reto,SANDHAM, David,
Andrew
珠海有什么大学申请号：EP01940294.0
lebritee申请日：20010405
公开号：EP1268480A1
clamp翻译>美国饮食习惯i walk this road alone公开日：
tonite
20030102
专利内容由知识产权出版社提供
摘要：\"Derived from 8 - isoquinolinxantina and 8 - quinolixantina as inhibitors of PDE 5.A compound of formula R ^ 1 ^ is hydrogen or alkyl optionally substituted by hydroxy, alc\u00f3xi, or alquiltio, R ^ 2 ^ is hydrogen, alkyl, hidroxialquila, alquilcarboniloxialquila, alcoxialquila,Alquiltioalquila, alquenila, cicloalquilalquila, heterociclilalquila,Aralquil in which the ring arila) is optionally fud to a Hetrocyclic group 5 elements or is optionally substituted by one or more substituents lected among amino, alc\u00f3xi,Alquilamino, dialquilamino, acylamino, halogen, hydroxy, aminossulfonila, alquilaminossulfonila, dialquilaminossulfonila, alquilsulfonilamino or dialquilaminossulfonilamino,R ^
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3 ^ is hydrogen or alkyl optionally substituted by hydroxy, alc\u00f3xi, or alquiltio, R ^ 4 ^ is hydrogen or alkyl, R ^ 5 ^ is a group quinolinila,Isoquinolinila or oxodiidroisoquinolinila optionally fud to a group of 5 elements and optionally Hetrocyclic replaced by one or more substituents lected among halogen, cyano,Hydroxy, alkyl, hidroxialquila,
alcoxialquila, alquiltioalquila, alc\u00f3xi, alquiltio, alquenila, alcoxicarbonila, alquinila, carboxyl, acyl, a group of the formula n (R ^ 6 ^) R ^ 7 ^.Arila optionally substituted by one or more substituents lected among halogen or alc\u00f3xi, or heteroarila having 5 or 6 atoms in the ring.Linked by a carbon atom of the ring to the carbon atom is indicated.And R ^ 6 ^ and R ^ 7 ^ are each independently hydrogen or alkyl optionally substituted by hydroxy or alc\u00f3xi or a R ^ 6 ^ and R ^ 7 ^ is hydrogen and the other is acyl,Or R ^ 6 ^ and ^ R ^ 7 together with the nitrogen atom to which they are connected with a group heterociclila 5 or 6 elements.
申请人：Novartis AG,Novartis-Erfindungen Verwaltungsgellschaft m.b.H.
shuping地址：Lichtstras 35 4002 Bal CH,Brunnerstras 59 1230 Wien AT
国籍：CH,AT
代理机构：Gros, Florent
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