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髓外造血（Extramedullaryhematopoiesis）
/articles/extramedullary-haematopoiesis
Extramedullary haematopoiesis is a respon to erythropoiesis failure in bone marrow. Extramedullary haematopoiesis occurs in haemoglobinopathies, myeloproliferative disorders, or bone marrow infiltration. It occurs most often in the spleen and liver and occasionally in the lymph nodes. Less common organs include the pleura, lungs, gastrointestinal tract, breast, skin, brain, kidneys, and adrenal glands.
髓外造血是骨髓红系造血功能衰竭的响应。髓外造血发生在血红蛋白病，骨髓增生性疾病或骨髓浸润性疾病。它大多发生在脾脏和肝脏，偶尔在淋巴结中出现。不常见的器官包括胸膜、肺、胃肠道、乳腺、皮肤、脑、肾和肾上腺。
Pathology
Aetiology
myeloproliferative disorders
chronic myelogenous leukemia
polycythemia vera
esntial thrombocytosis
myelofibrosis with myeloid metaplasia
haemoglobinopathies
sickle cell dia
thalasmia
在线英文词典病理
病因
没收英文
骨髓增生性疾病
．慢性粒细胞性白血病
．真性红细胞增多症
．原发性血小板增多症
sbr是什么．骨髓纤维化伴髓样化生
bem
血红蛋白病
just now．镰状细胞病
mprojector地中海贫血
Radiographic features
Where extramedullary haematopoiesis involves an organ, there is usually radiographic evidence of its enlargement, e.g. hepatomegaly, splenomegaly visualid by ultrasound, CT or MRI. However, in the less common situation where extramedullary haematopoiesis involves other tissues within the thorax, they can be en as aposterior mediastinal mass. The are paraspinal mass that may be unilateral or bilateral and have smooth,
sharply delineated, often lobulated margins.
影像学特征
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髓外造血器官，影像学上通常表现为器官增大，如超声、CT或MRI上表现为肝肿大、脾大。然而，在不常见的情况下，髓外造血可以发生在胸腔内，呈后纵隔肿块，变现为单侧或双侧脊柱旁肿块，边缘光滑，轮廓分明，常呈分叶状边缘。
病例图片：
tvries
satisfactory
图片来源：N Engl J Med 2010; 362:253
