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Chimeric LysR-Type Transcriptional Bionsors for Customizing Ligand Specificity Profiles toward
Flavonoids
汉堡英文期刊名称： ACS Synthetic Biology
作者： Brecht De Paepe,Jo Maertens,Bartel Vanholme,Marjan De Mey
年份： 2018年
宾语从句例句
xtm期号： 第2期
中英关键词： Escherichia coli;chimeric genetic circuits;flavonoids;ligand specificityarrive是什么意思
scissors是什么意思
郁郁寡欢什么意思engineering;transcriptional bionsors英汉翻译在线
摘要：Transcriptional bionsors enable key applications in both metabolic engineering and synthetic biology. Due to nature's immen variety of metabolites, the applications require bionsors with a ligand specificity profiles customid to the rearcher's needs. In this work, chimeric bionsors were
gmentedcreated by introducing parts of a donor regulatory circuit from Sinorhizobium meliloti, delivering the desired luteolin-specific respon, into a non-specific bionsor chassis from Herbaspirillum ropedicae. Two strategies were evaluated for the development of chimeric LysR-type bionsors with customid ligand specificity profiles towards three cloly-related flavonoids, naringenin, apigenin and luteolin. In the first strategy, chimeric promoter regions were constructed at the bionsor effector module, while in the cond strategy,...
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