芒果街上的小屋
贿赂英文
环球雅思培训多少钱Droplet digital PCR for the simultaneous analysis of minimal residual dia and hematopoietic chimerism after allogeneic cell transplantation
期刊名称： Clinical Chemistry & Laboratory Medicine
年份： 2019年在线课堂免费
家道殷实
期号： 第5期
诚然关键词： allogeneic hematopoietic cell transplantation;chimerism;droplet digital2011年12月四级
PCR;minimal residual dia
花菜的英文>cantone
摘要：Background Minimal residual dia (MRD) and hematopoietic chimerism testing influences clinical decision and therapeutic intervention in patients after allogeneic stem cell transplantation (HSCT). However, treatment approaches to induce complete donor chimerism and MRD negativity can lead to complications such as graft-versus-host dia (GvHD) and marrow aplasia. Therefore, there is a need for comprehensive characterization of the molecular remission status after transplantation. M
ethods We analyzed 764 samples from 70 patients after HSCT
for the simultaneous measurement of chimerism and molecular targets ud for MRD testing with a digital PCR (dPCR) platform. Results Mixed chimerism (MC) was detected in 219 samples from 37 patients. The mean percentage of host derived DNA in the clinical samples was 4.3%. Molecular relap
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