取长补短英文专利名称:SPLIT LUCIFERASE, AND HIGHLY SENSITIVE VITAMIN D RECEPTOR LIGAND DETECTION
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好消息英文发明人:SAKAKI, Toshiyuki,NISHIKAWA, Miyu,MANO, Hiroki
申请号:EP18873933365翻译
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orgasm是什么意思申请日:20181031
公开号:EP3705574A4
公开日:
20210929
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ref摘要:The prent invention pertains to any fusion protein in (1) to (3): (1) a fusion protein containing, in no particular order, the lucifera N-terminal domain (LucN), at least one vitamin D-binding domain of a vitamin D receptor (VDR), and the lucifera C-terminal domain (LucC), and able to additionally include, in no particular order, an
LX1X2LL quence and/or a linker quence; (2) a fusion protein containing, in no particular order, LucN or LucC, and an LX1X2LL quence, and able to additionally include, in no particular order, a linker quence; and (3) a fusion protein containing, in no particular order, at least one vitamin D-binding domain of a VDR, and LucC or LucN, and able to additionally include, in no particular order, a linker quence. The prent invention also pertains to a method for screening, using the fusion protein, for substances which demonstrate the ability to bind to VDRs. The prent invention provides a bionsor in which the luminescence increas when an agonist binds thereto, and provides a method for easily screening for substances which bind strongly to vitamin D receptors (V
DRs).2011辽宁高考英语
申请人:Public University Corporation Toyama Prefectural University 更多信息请下载全文后查看
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