专利名称：Methods for identifying chemicals that act as agonists or antagonists for receptors and
jingle bellother proteins involved in signal
transduction via pathways that utilize G-
proteins
发明人：Michael R. Lerner,Ethan A. Lerner
申请号：US08/479121
申请日：19950607
公开号：US06051386A
公开日：sheltered
穿井得人翻译
20000418august怎么读
gprs
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摘要：A method for identifying a chemical that acts as an agonist for a G- protein coupled cell surface (GPC) receptor. The method compris introducing to test cells of a pigment cell line capable of dispersing or aggregating their pigment in respon to a specific stimulus and expressing an exogenous clone coding for the GPC receptor, a stimulant that ts an initial state of pigment disposition wherein the pigment is aggregated within the test cells if activation of the exogenous GPC receptor induces pigment dispersion, or introducing a stimulant that ts an initial state of pigment disposition wherein the pigment is disperd within the test cells if activation of the exogenous GPC receptor induces pigment aggregation; contacting the test cells t in an initial state of pigment disposition with the test chemical; and determining whether the pigment disposition in the test cells treated with the chemical is changed from the initial state of pigment disposition, wherein a change in pigment disposition obrved in the test cells expressing the exogenous GPC receptor indicates that the chemical is anlevis
稀罕的近义词是什么>analy过去式agonist for the exogenous GPC receptor.
smart是什么意思申请人：BUNSEN RUSH LABORATORIES, INC.
代理机构：Wolf, Greenfield & Sacks, P
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