目录
中文摘要 (1)
英文摘要 (3)
英文缩写 (5)
study的过去分词研究论文一关于外科颞浅(STA)-大脑中动脉(MCA)搭桥术对成人烟雾病患者短期脑血流动力学变化的研究
前言 (6)
材料与方法 (6)
结果 (8)
讨论 (10)
结论 (11)
在职研究生如何报名研究论文二关于外科颞浅(STA)-大脑中动脉(MCA)搭桥术对成人烟雾病患者认知功能变化的研究
前言 (12)
材料与方法 (12)
结果 (13)
讨论 (16)
结论 (17)
参考文献 (17)
综述成人烟雾病患者搭桥术前后灌注成像及认知功能的研究进展 (21)
致谢 (34)
个人简历 (35)dareyou
关于颞浅（STA）-大脑中动脉（MCA）搭桥术对成人烟雾病患者短期脑血流动力学及认知功能变化的研究
求职意向英文摘要
障碍滑雪目的：利用CT灌注(Computed tomography perfusion,CTP)、CT血管成像（Computed tomography angiography ,CTA）、简易精神状态量表(M ini-Mental State Examination，MMSE）、蒙特利尔认知评估量表(Montre al Cognitive Asssment，MOCA)评价外科颞浅（STA）-大脑中动脉(MC A)搭桥术对成人烟雾病患者短期脑血流动力学及认知功能的影响。
方法：选取30例经DSA确诊为烟雾病的住院患者作为观察对象。所有患者均行单侧STA-MCA搭桥术，并于术前及术后一周行DSA、CTP 及CTA等影像学检查；测量术侧大脑中动脉（MCA）分布区和对侧镜像对照区的灌注参数，包括脑血流量（CBF）、脑血容量（CBV）、达峰时间（TTP）和平均通过时间（MTT），得到了相对CTP值（rCBV、rCBF、rTTP、rMTT）。并在术前一周和术后3个月进行MOCA、MMSE两项神经认知功能测试。
结果：
1.30例成人烟雾病患者术后CTP示脑血流均有不同程度改善，搭桥术后手术侧大脑中动脉分布区与对侧镜像区的rCBF、rCBV高于术前，rMTT、rTTP低于术前，P<0.05。所有患者术后CTA均显示桥血管吻合口形态良好，分支血管通畅、充盈良好，管壁光滑。
2.30例成人烟雾病患者颞浅-大脑中动脉搭桥术术后三个月MOCA及MMSE评分均较术前有所改善，P<0.05。
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结论：
1.外科颞浅（STA）-大脑中动脉(MCA)搭桥术能有效改善成人烟雾病患者短期脑血流动力学；
2.CTP联合CTA可有效指导成人烟雾病手术方式、评价术后脑灌注状态改变情况及桥血管的通畅情况；
长沙室内设计培训3.外科颞浅（STA）-大脑中动脉(MCA)搭桥术能改善成人烟雾病患者短期认知功能。
nobles关键词：颞浅-大脑中动脉搭桥术，烟雾病，CTP，认知功能，MOCA，MMSE
norm
Study on the Superficial Temporal Artery(STA) -Middle Cerebral Artery (MCA) Bypass for the Changes on Short-term Cerebral Hemodynamics and Cognitive Function in Adults with
Moyamoya Dia
ABSTRACT
Objective: To u Computed tomography perfusion (CTP), Computed tomography angiography (CTA), Mini-Mental State Examination (MMSE), Montreal Cognitive Asssment (MoCA) To evaluate
the effect of surgical superficial temporal artery (STA) -middle cerebral artery (MCA) bypass on short-term cerebral hemodynamics and cognitive function in adult patients with moyamoya dia.
Methods:Thirty inpatients diagnod with moyamoya dia by DS A were lected as obrvation objects. All patients underwent unilateral STA-MCA bypass surgery, and DSA, CTP, and CTA imaging examina tions were performed before and after one week of the operation; the perfusion parameters of the middle cerebral artery (MCA) distribution ar ea on the surgical side and the contralateral mirror control area were m easured ,Including cerebral blood flow (CBF), cerebral blood volume (C BV), time to peak (TTP) and mean transit time (MTT), the relative C TP values (rCBV, rCBF, rTTP, rMTT) were obtained. Two neurocogniti ve tests of MoCA and MMSE were performed one week before and 3 months after surgery.
capitalizationResults：
1.30 cas of adult moyamoya dia patients showed different degrees of improvement in cerebral blood flow after surgery. The rCBF and rCBV of the middle cerebral artery distribution area and the contralateral mirror area after bypass surgery were higher than before surgery, and rMTT and rTTP were lower than tho before surgery,P <0.05. Postoperative CTA showed that the anastomosis of the bridge vesl was good, the branch vesls were
smooth and filling, and the wall was smooth.
2. MoCA and MMSE scores of 30 patients with moyamoya dia in the superficial temporal artery-middle cerebral artery bypass graft were improved compared with tho before surgery,P<0.05.
Conclusions:
1. Surgical superficial temporal artery(STA)-middle cerebral artery (MCA) bypass surgery can improve short-term cerebral he-modynamics i n adults with moyamoya dia;
2. CTP combined with CTA can effectively guide the surgical methods of adult moyamoya dia, evaluate the changes of postoperative cerebral perfusion status and the patency of bridge vesls;
3. Surgical superficial temporal artery(STA)-middle cerebral artery (MCA) bypass surgery can improve short-term cognitive function in adults with moyamoya dia.
Keywords:Superficial temporal artery-middle cerebral artery bypass surgery, Moyamoya dia, CTP, Cognitive function, MOCA, MMSE
