WHO国际药物监测中心对可疑不良反应的因果

更新时间:2023-06-15 21:55:16 阅读: 评论:0

  WHO国际药物监测中⼼对可疑不良反应的因果关系如何分级?
  WHO国际药物监测中⼼将可疑不良反应的因果关系分成如下级别:
  1.certain
  2.probable/likelyweirdest
innocence歌词翻译
新视野大学英语3课文翻译  3.possible
  4.unlikely
怎么样才能祛斑  5.conditional/unclassified
  6.unasssible/unclassifiable
  实际上,主要是4级,即肯定(certain),很可能(probable/likely),可能(possible),不太可能(unlikely)。conditional/unclassified和unasssible/unclassifiable均不属于因果关系的正式术语,前者是指报告资料有待作进⼀步的补充和评价,然后再决定其级别;后者是由于报告资料不考试,⼤站收集⾜或存在⽭盾⽽⽆法评价。WHO因果关系评价的具体内容如下:
  CERTAIN
  A clinical event, including laboratory test abnormality, occurring in a plausible time relationship to drug administration, and which cannot be explained by concurrent dia or chemicals. The respon to withdrawal of the drug (dechallenge) should be clinically plausible. The event must be definitive pharmacologically or phenomenological,using a satisfactory rechallenge procedure if necessary.
  PROBABLE/LIKELY举世闻名是什么意思
  A clinical event, including laboratory test abnormality, with a reasonable time quence to administration of the drug, unlikely to concurrent dia or other drugs or chemicals, and which follows a clinically reasonable respon in withdrawal (dechallenge)。 Rechallenge information is not required to fulfil this definition.
英语改错题
  POSSIBLE
平台是什么意思>珠海 大学  A clinical event, including laboratory test abnormality, with a reasonable time quence to administration of the drug, but which could also be explained by concurrent dia or other drugs or chemicals. Information on drug withdrawal may be lacking or unclear.
  UNLIKELY
parated
  A clinical event, including laboratory test abnormality, with a temporal relationship to drug administration which makes a causal relationship improbable, and in which other drugs, chemicals or underlying dia provide plausible explanations.
  CONDITIONAL/UNCLASSIFIED
  A clinical event, including laboratory test abnormality, reported as an adver reaction, about which more data is esntial for a proper asssment or the additional data are under examination.oppo手机广告曲
  UNASSESSIBLE/UNCLASSIFIABLE
  A report suggesting an adver reaction which cannot be judged becau information is insufficient or contradictory,and which cannot be supplemented or verified.

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