Comparison of racemic ketamine and S-ketamine in t

更新时间:2023-06-14 01:00:11 阅读: 评论:0

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说英文>cody
Comparison of racemic ketamine and S-ketamine in treatment-resistant major depression: Report of
two cas
期刊名称: World Journal of Biological Psychiatry
作者: Robert Paul,Nadine Schaaff,Frank Padberg,Hans-Jürgen Möller,Thomas
Frodl
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年份: 2009年
gallery期号: 第3期
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关键词: Treatment-resistant depression;ketamine;S-ketamine;NDMA
lunch是什么意思antagonists
摘要:Recent studies with intravenous infusion of the NMDA receptor antagonist ketamine showed rob
ust and rapid antidepressant effects within hours after treatment. Ketamine is a racemic mixture consisting of two enantiomers, R- and S-ketamine. In contrast to ketamine, S-ketamine is reported to be less prone to psychomimetic side effects, such as derealisation and hallucinations. In this reportsake
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缨尾目we describe the effect of ketamine and S-ketamine infusion therapy, respectively, in two patients with treatment-resistant major depression. Severity of depression was rated using the Hamilton Depression Rating Scale (HAMD) and the Beck Depression Inventory (BDI). While one patient did not respond to either treatment, in the other patient intravenous administration of ketamine as well as S-ketamine showed an antidepressant effect as assd
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