专利名称：Derivatives of perhydro-aza-heterocycles 发明人：Romeo Paioni
toefl报名流程申请号：US05/827274
四级技巧申请日：19770824
董事长助理英文公开号：US04160837A
公开日：
higgs boson
19790710
专利内容由知识产权出版社提供
mona lisa smile>noon是什么意思摘要：The prent invention provides new derivatives of perhydro-aza- heterocycles of the formula ##STR1## in which X is the oxo radical or hydrogen and the radical
OR.sub.1, in which R.sub.1 is hydrogen or a substituted or unsubstituted aliphatic hydrocarbon radical, a substituted or unsubstituted araliphatic hydrocarbon radical or a substituted or unsubstituted aromatic hydrocarbon radical or an acyl radical, R.sub.2 is hydrogen or a substituted or unsubstituted aliphatic hydrocarbon radical, Y is oxygen or sulphur, n.sub.1 and n.sub.2 each are values of 1 to 3, n. sub.1 +n.sub.2 being at most four, and Ar is a substituted or unsubstituted aromatic hydrocarbon radical, and the acid addition salts, in particular the pharmaceutically acceptable acid addition salts thereof. The new substances posss valuable pharmacological properties, in particular antidepressant activity, and can be ud for the treatment of mental depressions. Specific embodiments are trans- and cis-3-hydroxy-4- (3,4-dimethyl-phenoxy)-piperidine, trans-and cis-3-hydroxy-4-(2,3- dimethyl-phenoxy)-piperidine, their 1-methyl derivatives and the pharmaceutically acceptable salts of the substances.
申请人：CIBA-GEIGY CORPORATION
代理人：John J. Maitner
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怎么处对象>ddgs
