beautiful danceLinking CMV rostatus to episodes of CMV reactivation following lung transplantation by measuring CMV-specific CD8+ T-cell immunity 期刊名称: American Journal of Transplantation
作者: G P Westall,NA Mifsud,T Kotsimbos
年份: 2010年
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anyclub生活大爆炸6关键词: CD8;CMV;lung transplantation;T-cell immunityovation
摘要:CMV-specific immunity was assd in a longitudinal cohort of 39 lung transplant recipients (LTR) who were followed prospectively from the time of transplant using a novel assay. At the time of surveillance bronchoscopy, CMV-specific CD8 + T-cell respons were assd in the peripheral blood, using the QuantiFERON ® -CMV assay, which measures IFN-γ-creting T cells following stimulation with CMV peptides. In total, 297 samples were collected from 39 LTR (CMV D+/R−, n = 8; D+/R+, n = 18; D−/R+, n = 6; D−/R−, n = 7). CMV-specific T-cell immunity was not detected in any of th可笑的>高中军训
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cret是什么意思e CMV D−/R− LTR. In CMV ropositive LTR levels of CMV immunity were lowest early posttransplant and incread thereafter. While levels of CMV-specific immunity varied between LTR, measurements at any one time point did not predict episodes
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