primadonnaFRI0246Serious infusion-related reactions after rituximab in patients with rheumatoid arthritis: data from the autoimmunity and rituximab registry 期刊名称： Annals of the Rheumatic Diasrelationship
assumed作者： J. H. Salmon,P. Ravaud,T. Bardin,P. Cacoub,A. Cantagruel,B. Combe,M.
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pickleDougados,R.-M. Flipo,B. Godeau,L. Guillevin,X. Le Loët,E. Hachulla,T.
aloeSchaeverbeke,J. Sibilia,I. Pane,G. Baron,X. Mariette,J.-E. Gottenberg
融合英文年份： 2013年
期号： 第Suppl 3期
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摘要：ObjectivesTo evaluate the prevalence of rious infusion-related reactions after rituximab (RTX) in a large prospective registry of patients with rheumatoid arthritis.MethodsThe Autoimmunity and Rituximab registry (AIR) is an independent registry promoted by the French Society of Rheumatology that included 1983 patients with rheumatoid arthritis treated with rituximab and followed-up prospectively for ven years. An infusion-related reaction (IRR) was defined as occurring during or in t樟属
he 24 hours following an infusion.ResultsOverall, 45 IRR resulted in RTX discontinuation [2.2% of all patients with RA, 0.4% of all infusions]. The rious IRR occurred after the first cycle in 17 patients, the cond cycle in 18, the third cycle in 7, the fourth cycle in 2 patients and after the fifth cycle in 1 patient. Serious IRR
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