Sequential expression and differential localization of I-, L-, and T-Fimbrin during differentiation of the mou intestine and yolk sac (p141-151)期刊名称： Developmental Dynamics
作者： Mark,M.,Chafel,Wenyan,Shen,Paul,Matsudaira
lo you曼德拉手语翻译年份： 2010年germany
浦东大拇指广场期号： 第2期
在线中英文转换器
关键词： Fimbrin;Plastin;Intestinal epithelium;Visceral
snakeendoderm;Microvilli;Adhesion;Actin;Development;Embryogenesis
jedward>handspring摘要：During the differentiation of the intestine epithelium, three cytoskeletal proteins, villin, fimbrin, and myosin I, are quentially expresd and localized to the apical membrane. Recently, we found that in the adult mou and human, three fimbrin isoforms are expresd in a cell specific manner. I-fimbrin is expresd by intestine and kidney epithelial cells, L-fimbrin is expresd by leukocytes and many tumors, while T-fimbrin is expresd by various cells and tissues. Becau non-intestinal isoform
世博演艺中心
s of fimbrin could be expresd early in development, the expression of fimbrin isoforms during days 10.5 to 16.5 of intestine development
was investigated. By immunofluorescence microscopy, T-fimbrin was detected in the early stages of intestinal epithelial cell differentiation until day 14.5 and was localized predominantly at
启发式
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