emba培训专利名称:QUINAZOLINE-3-ALKANOIC ACID高中数学教材人教版
DERIVATIVE, SALT THEREOF, AND
PRODUCTION THEREOFdisrupt
发明人:FUJIMORI, Shizuyoshi,OHNOTA,
Michiro,HIRATA, Yoshihiro,MURAKAMI, Koji 申请号:EP91900052.1苹果最新广告歌曲
申请日:19901210
公开号:EP0456835A1
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公开日:
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blink摘要:A quinazoline-3-alkanoic acid derivative of general formula (I), which has both of platelet agglutination inhibition and aldo reducta inhibition activities, salts thereof, process for producing the same, and a medicine containing the same, wherein R reprents hydrogen or a protective group of the carboxyl group; R' reprents lower alkyl, alkenyl, alkynyl, lower alkoxy, lower alkylthio, halogen, phenyl (which may be substituted with 1 to 3 substituents lected from among lower alkyl, lower alkoxy, halogen, trifluoromethyl, carboxyethylene, and ethoxy-carbonylethylene groups), naphthyl, heterocycle (which may be substituted with 1 to 3 lower alkyl groups), cycloalkyl, or benzoyl (which may be substituted with lower alkyl or halogen); R² and R³may be the same or different from each other and each reprents hydrogen, halogen, lower alkyl, lower alkoxy, optionally substituted aralkyl, nitro, imidazolyl, imidazolylmethyl, or -NR⁴R⁵ wherein R⁴ and R⁵ may be the same or different from each other and each reprents hydrogen or lower alkyl, or they are combined with each other to form a 5- or 6-membered heterocycle which may contain other heteroatom(s); X
reprents carbonyl, thiocarbonyl or methylene (which may be substituted with lower alkyl); A reprents lower alkylene or lower alkenylene; and n is an integer of 1 to 3.
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申请人:KYORIN PHARMACEUTICAL CO., LTD.
地址:No. 5, Kanda Surugadai 2-chome Chiyoda-ku Tokyo JP
国籍:JP
代理机构:TER MEER - MÜLLER - STEINMEISTER & PARTNER
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