专利名称：Koshokuzai
发明人：NITSUCHI YASUTAKE 申请号：JP26386786
申请日：19861107
wake wake
公开号：JPH0233685B2csf
窘态>英语四级听力答案defected公开日：
19900730
专利内容由知识产权出版社提供
德国人名
bullshit摘要：PURPOSE:To obtain an anticarious substance, consisting of purified gymnemic acid prepared from Gymnema sylvestre, having high inhibitory effects on formation of bacterial plaques and capable of remarkably suppressing growth of cariogenic bacteria. CONSTITUTION:Dried leaves of Gymnema sylvestre are extracted with hot water and the resultant extract solution is adjusted to pH3 with 2N sulfuric acid to provide precipitates containing crude gymnemic acid. The precipitates are collected by centrifugal ttling and the aggregates are washed with water and extracted with ethanol. The extract is then concentrated under reduced pressure and acetone in a volume of 2 times is added to the concentrate to carry out centrifugal ttling. The supernatant liquid is subquently concentrated to dryness under reduced pressure and extracted with diethyl carbonate as a solvent as the boiling point. Substances deposited from the above-mentioned solvent are collected and evaporated to dryness, subjected to high-speed liquid chromatography to afford the aimed purified gymnemic acid. The resultant purified gymnemic acid has action of inhibiting formation of glucan by cariogenic bacteria as well as surely preventing formation of bacterial plaques and is preferably ud by containing in an amount of
>=10mM.
上海环球雅思怎么样申请人：NITSUCHI YASUTAKE
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