蛋白酶切位点

更新时间:2023-05-20 13:16:54 阅读: 评论:0

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Enzymes
E.C. Number
Cleavage sites
Serine proteas
E.C.3.4.21.
 
α-chymotrypsin(胰凝乳蛋白酶,糜蛋白酶)
E.C.3.4.21.1
Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, and also Leu-|-Xaa, Met-|-Xaa,
Trypsin (胰朊酶,胰蛋白酶)
E.C.3.4.21.4
Arg-|-Xaa, Lys-|-Xaa,
Pancreatic elasta(胰弹性蛋白酶)
E.C.3.4.21.36
Ala-|-Xaa,and also Gly-|-Xaa, Val-|-Xaa, Ser-|-Xaa,
Thrombin(凝血酶)
E.C.3.4.21.5
Arg-|-Gly,
Plasmin(胞质素,胞浆素)
E.C.3.4.21.7
Lys-|-Xaa,> Arg-|-Xaa
Prolyl oligopeptida,or prolyl endopeptida
E.C.3.4.21.26
Pro-|-Xaa,>> Ala-|-Xaa
Plasma kallikrein(血浆激肽释放酶)
E.C.3.4.21.34
Arg-|-Xaa, Lys-|-Xaa,including Arg-|-Ser, Lys-|-Arg,
Leukocyte elasta(白细胞弹性蛋白酶
),or neutrophil elasta(中性白细胞弹性蛋白酶),or lysosomal elasta(溶酶体弹性蛋白酶)
E.C.3.4.21.37
Val-|-Xaa, Ala-|-Xaa,
Cysteine proteas
E.C.3.4.22.
 
Cathepsin B(组织蛋白酶)
E.C.3.4.22.1
Arg-Arg-|-Xaa, and also Leu-|-Xaa, Ala-|-Xaa, Phe-|-Xaa, Trp-|-Xaa,
Clostripain(梭菌蛋白酶),or endoproteina Arg-C
E.C.3.4.22.8
Arg-|-Xaa including Arg-|-Pro,but not Lys-|-Xaa
Calpain(钙激活中性蛋白酶)-1,or μ-calpain
E.C.3.4.22.52
Met-|-Xaa, Tyr-|-Xaa and Arg-|-Xaa(with Leu or Val as the P2 residue)
Aspartic acid proteas
E.C.3.4.23.
 
Pepsin(胃朊酶,胃蛋白酶)
E.C.3.4.23.1
Preferentially Phe-|-Xaa, Tyr-|-Xaa, and also Leu-|-Xaa,and Trp-|-Xaa,,ideally with Xaa= Phe,Trp,or Tyr
Cathepsin(组织蛋白酶)D
E.C.3.4.23.5
Preferentially Phe-|-Xaa, Tyr-|-Xaa, and also Leu-|-Xaa, ideally with Xaa ≠ Ala or Val
Metalloproteas
E.C.3.4.24.
 
Neprilysin(脑啡肽酶),or enkephalina(脑啡肽酶),or neutral endopeptida
E.C.3.4.24.11
Xaa-|-Tyr, Xaa-|-Phe, Xaa-|-Trp, and Xaa-|-Leu,
Thimet oligopeptida(甲拌磷寡肽酶),or endo-oligopeptida A,or endopeptida(肽链内切酶)24.15,or pz-peptidea(肠促胰酶素)
E.C.3.4.24.15
Xaa-|-Arg, Xaa-|-Ser, Xaa-|-Ile, Xaa-|-Ala, Xaa-|-Gly,
Aminopeptidas
E.C.3.4.11.
N-term
Leucyl-aminopeptida
E.C.3.4.11.1
Preferentially Leu-|-Xaa,but not Arg-|-Xaa,and Lys-|-Xaa,
Aminopeptida M or N,or alanyl- aminopeptida,or membrane alanine aminopeptida
E.C.3.4.11.2
Preferentially Ala-|-Xaa,and Tyr-|-Xaa,if Yaa-Pro-|-Xaa in term with Yaa = Ala,Val,Leu,Ile,Phe,Tyr or Trp,then the dipeptide Yaa-Pro could be relead
Aminopeptida B
E.C.3.4.11.6
Arg-|-Xaa, Lys-|-Xaa,
Aminopeptida A,or angiotensina,or glutamyl-aminopeptida
E.C.3.4.11.7
Glu-|-Xaa>> Asp-|-Xaa,
Dipeptidyl-peptidas and tripeptidyl-peptidas
E.C.3.4.14.
N-term(di-and tripeptides)
高考语文题
Dipeptidyl-peptida I,or cathepsin(组织蛋白酶) C or J
E.C.3.4.14.1
Xaa-Yaa-|-Zaa,if Xaa ≠ Arg or Lys,or Yaa  ≠ Pro,or Zaa ≠ Pro
Dipeptidyl-peptida IV
E.C.3.4.14.5
Preferentially Xaa-Pro-|-Zaa,(but also Xaa-Ala-|-Yaa) with Yaa ≠ Pro or Hyp
Prolyl tripeptyl-peptida
E.C.3.4.14.12
Xaa-Yaa-Pro-|-Zaa,if Zaa ≠ Pro
Peptidyl-Dipeptidas
E.C.3.4.15.
词汇大全C-term
Peptidyl-depeptida A, or angiotensin-converting enzyme
E.C.3.4.15.1
Xaa-|-Yaa-Zaa,if Yaa ≠ Pro or Zaa ≠ Asp or Glu
Metallo-carboxypeptidas
E.C.3.4.17.
C-term
Carboxypeptida A
E.C.3.4.17.1
Xaa-|-Yaa if Yaa ≠ Asp,Glu,Arg,Lys or Pro
Carboxypeptida B,or protamina
E.C.3.4.17.2
Xaa-|-Arg and Xaa-|-Lys
Carboxypeptida N,or Lysine(arginine), Carboxypeptida(羧基肽酶),or kinina I(激肽酶)
E.C.3.4.17.3
Xaa-|-Lys>> Xaa-|-Arg
生气用英语怎么说
Carboxypeptida U or Rdresden
E.C.3.4.17.20
Xaa-|-Arg and Xaa-|-Lys
Glutamate Carboxypeptida II,or folate hydrola
E.C.3.4.17.21
Xaa-|-Glu,preferentially with Xaa= Asp or Glu

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