麦青青
Prevalence and caus of abnormal PSA recovery 期刊名称： Clinical Chemistry and Laboratory Medicine (CCLM)
楼梯的组成
年份： 2018年
陌上桑
龙猫吃什么期号： 第2期大香山
关键词： autoantibodies;heterophilic antibodies;immunoassay;prostate-specific antigen (PSA);prostate;recovery
秋姑娘摘要：Prostate-specific antigen (PSA) test is of paramount importance as a diagnostic tool for the detection and monitoring of patients with prostate cancer. In the prence of interfering factors such as heterophilic antibodies or anti-PSA antibodies the PSA test can yield significantly falsified results. The prevalence of the factors is unknown.We determined the recovery of PSA concentrations diluting patient samples with a standard rum of known PSA concentration. Bad on the frequency distribution of recoveries in a pre-study on 268 samples, samples with recoveries 120% were defined as suspect, re-tested and further characterized to identify the cau of interference.A total of 1158 cons
ecutive rum samples were analyzed. Four samples (0.3%) showed reproducibly disturbed recoveries of 10%, 68%, 166% and 4441%. In
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