南京体育学院学报
2020年 06月
第17卷第3期
生物骨科材料与临床研究O rthopaedic B iomechanics M aterials A nd C linical S tudy .11.
五年级语文阅读
doi: 10.3969/j.issn. 1672-5972.2020.03.003
文章编号：swgk201头10-00216骨髓富集骨移植材料在青少年特发性脊柱侧弯矫治中的应用*
*基金项目：重庆市基础与前沿研究计划项目(CSTC2015jcyjA100⑸；西南医
香干回锅肉的做法院临床科研专项(SWH2014LC06)；国家重点研发计划(2017YFC1103304) 作者单位：陆军军医大学第一附属西南医院骨科，重庆,400038杨鹏 侯天勇 邢军超 罗飞 许建中*
［摘要］目的比较骨髓富集骨移植材料和同种异体骨作为骨移植材料用于青少年特发性脊柱侧弯(AIS)矫治中 的临床疗效。方法自2014年7月至2016年9月，前瞻性选取31例青少年特发性脊柱侧弯Lenke I 患者，按 随机数表法将患者随机分为对照组(14例)与观察组(17例)，其中对照组釆用同种异体骨作为植骨融合材料， 观察组采用骨髓富集骨移植材料作为植骨融合材料。术后随访24个月，对两组患者的手术时间、术中出血量、 住院时间、主弯矫正率、矫正丢失、融合率、VAS 评分、ODI 评分、SRS-30评分、
并发症发生情况进行比较。 结果两组手术时间、术中出血量、住院时间、矫正率、矫正丢失比较差异无统计学意义(P>0.05)o 所有患者末 次随访时VAS 评分、ODI 评分、SRS ・30评分均优于术前，但两组间术前与末次随访差异均无统计学意义(P>0.05)o 术后6个月观察组融合率高于对照组，末次随访时观察组脊柱融合Lenke 分级情况略优于对照组。观察组出现 术后伤口愈合不良1例，无其他并发症。结论骨髓富集骨移植材料是一种安全、有效、易构建的植骨材料，用 于脊柱融合可获得优于同种异体骨的融合效果。夏威夷果吃多了会怎么样
［关键词］青少年特发性脊柱侧弯；骨髓富集技术；同种异体骨；脊柱融合
［中图分类号］R682.3 ［文献标识码］B
Bone marrow enrichment bone graft material in the treatment of adolescent idiopathic scoliosis清潭菩萨
Yang P eng, Hou Tianyong, Xing J unchao, LuoFei, XuJianzhong. Department of O rthopedics, The First A ffiliated Hospital of t he Army M edical University, Chongqing, 400038, China
［Abstract ］ Objective To compare the clinical efficacy of bone marrow enrichment bone graft material and allogeneic bone as bone graft materials in adolescent idiopathic scoliosis (
正宗广东猪肚鸡的配方
爆炒南瓜AIS). Methods From July 2014 to September 2016, thirty-one patients with Lenke I-III type AIS were prospectively lected and randomly divided into control group (14 cas) and obrvation group (17 cas). Allogeneic bone was ud in control group as bone graft fusion material, and the bone marrow enrichment bone graft material was ud in obrvation group as bone graft fusion material. All patients were followed up for 24 months, and the perioperative parameters, imaging findings, clinical scores, and complications were compared between the two groups. Results There were no significant differences in operation time, intraoperative blood loss, hospital stay, correction rate, and correction loss between the two groups (Z^>0.05). The VAS score, ODI score and SRS-30 score of a ll patients were superior to preoperative at the last follow-up, but there was no significant dif ference between the two groups before and after surgery. The fusion rate in the obrvation group was higher than that in the control group at 3 months and 6 months after operation. At the last follow-up, the Lenke classification of t he spinal fusion in the obrvation group was slightly better than that of the control group. There was one ca of poor wound healing in the obrvation group, and no other complications were obrved. Conclusion Bone marrow enrichment bone graft material is a safe, effective and easy to construct bone graft material, which can be ud for spinal fusion to achieve better fusion effect than allogeneic bone.
橘子老虎
［Key words ］ Adolescent idiopathic scoliosis; Bone marrow enrichment technique; Allogeneic bone; Spinal fusion 青少年特发性脊柱侧弯(adolescent idiopathic scoliosis, AIS)是在青少年时期出现的原因不明的非先天性三维脊柱
畸形，总体发病率为1%〜3%，其中超过0.02%的患者需 要手术治疗［1,o 随着AIS 手术治疗理念的不断更新，矫形
内固定加植骨融合术已成为临床应用最广泛且疗效最确切的
外科治疗方法，AIS 的手术治疗不仅依靠器械矫形，更关键
在于术后固定节段的牢固融合叫自体骨被认为是脊柱融合 术中骨移植材料的“金标准”叫但伴有骨丢失、神经损伤、 持续性疼痛、感染等供区并发症叫 尤其对于Lenke 分型 为I -皿型的AIS 患者来说，术中通常不需要切除肋骨，术 中获得的自体骨不能满足植骨需要，且青少年骨发育可能还 未完全成熟，取自体骼骨容易破坏骨聽。同种异体骨虽无自 体取骨的并发症，但经处理后骨诱导活性和生物力学性能降
