专利名称:RNA targeted 2′-modified
oligonucleotides that are conformationally
preorganized
发明人:Muthiah Manoharan,Venkatraman
师夷长技以制夷Mohan,Herb Boswell
隆山塔美国的英语怎么说申请号:US09123108
申请日:19980727集中学习
公开号:US06271358B1青椒黄瓜
走路能减肚子吗
公开日:
中介代理
20010807
专利内容由知识产权出版社提供
摘要:2′-O-modified ribosyl nucleosides and modified oligonucleotides containing such nucleotides are disclod. Oligonucleotides are disclod that have incread binding affinity as shown by molecular modeling experiments. The 2′-O-modified nucleosides of the invention include ring structures that position the sugar moiety of the nucleosides preferentially in 3′ endo geometries.
申请人:ISIS PHARMACEUTICALS, INC.
西安事变纪念馆代理机构:Woodcock Washburn Kurtz Mackiewicz & Norris LLP
更多信息请下载全文后查看