Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in
LDLr-/- mice.618和双十一哪个优惠力度大
怎么制作表格教程期刊名称： Annals of the Rheumatic Dias
杨字开头的成语作者： Wilhelm, A. J.,Rhoads, J. P.,Wade, N. S.,Major, A. S.
北朝鲜高级卖春女年份： 2015年
双桂山期号： 第4期
项目的特征
摘要：ObjectiveAccelerated atherosclerosis is a major source of morbidity in systemic lupus erythematosus (SLE). However, the cau of SLE-accelerated atherosclerosis remains unclear.MethodsCD4+ T cells from C57/Bl/6 (B6) or SLE-susceptible B6.Sle1.2.3 (B6.SLE) mice were transferred into LDLr/, Rag/ mice. T cells were examined for cytokine production and expression of interleukin-10 receptor (IL-10R) and functional markers. T cells were isolated bad on FoxP3GFP expression and transferred to LDLr/, Rag/ mice to establish a role for B6.SLE effector T cells (Teff) in at
让梦想照进现实
herosclerosis.ResultsMice receiving whole B6.SLE CD4+ T cells displayed no other SLE phenotype; however, atherosclerosis was incread nearly 40%. We noted dysregulated IL-17 production and reduced frequency of IL-10R expression by B6.SLE regulatory T cells (Treg).
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