氧氟沙星片Non-adherence in difficult asthma: time to take it
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期刊名称： Thorax
作者： Heaney, L. G., Horne, R.
年份： 2012年
9月7日是什么星座期号： 第3期
写鬼写妖高人一等关键词： Humans;Asthma;Anti-Asthmatic Agents;Drug Monitoring;Medication Adherence;Glucocorticoids
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摘要：Recent studies have demonstrated a high prevalence of non-adherence with anti-inflammatory medication in patients referred for specialist asssment with difficult-to-control asthma. As well as poor asthma outcome and incread healthcare cost, failure to detect non-adherence makes identificat
英语语句
ion of true treatment-resistant/refractory asthma challenging. This is becau guideline definitions of refractory asthma are all predicated on failure to respond to high-do anti-inflammatory therapy but do not state how adherence with this therapy should be assd. With the advent of novel expensive biological therapies, the systematic identification of non-adherence becomes more esntial to avoid targeting therapies at an inappropriate patient group. Novel biomarkers of steroid exposure, in combination with more traditional
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