藏药唐古特乌头总生物碱的急性毒性及抗炎镇痛作用
家电产业
删除文本框目的：研究藏药唐古特乌头总生物碱（TAA）的急性毒性及抗炎镇痛作用。方法：采用灌胃和腹腔注射两种给药途径研究TAA的急性毒性；采用二甲苯致小鼠耳肿胀、琼脂肉芽肿两种炎症模型，考察TAA的抗炎作用；采用冰醋酸致小鼠扭体和热板致痛两种疼痛模型，观察TAA的镇痛作用。结果：TAA具有一定急性毒性，对二甲苯致小鼠耳肿胀和皮下琼脂肉芽肿两种炎症模型以及冰醋酸致小鼠扭体和热板致痛两种疼痛模型均有一定的抑制作用。结论：藏药唐古特乌头总生物碱具有抗炎镇痛作用，也具有一定的急性毒性。甜玉米
标签：唐古特乌头；生物碱；急性毒性；抗炎镇痛
Acute Toxicityand Anti-inflammatoryor Analgesic Effects of Total Alkaloids of Aconitum Tanguticum in Mice
照片艺术
WU Guotai 1， 2NIU Tinghui 1LIU Wuzhou1WANG Ruiqiong1DU Lidong1， 2LI Guang yuan 1*
1 Gansu University of Chine Medicine， Lanzhou 730000， China； 2 Key Laboratory
零件英文
扫把of Pharmacology and Toxicology of Traditional Chine Medicine in Gansu province， Lanzhou 730000， China
Abstract： Objective To study the acute toxicityand anti-inflammatoryor analgesic effectsoftotal alkaloids of Aconitum tanguticum（Maxim）stapf（TAA） through experiments Methods Acute toxicity of TAA were measured by using oral and intraperitoneal injection of routes of administration The anti-inflammatory effects of TAA were obrved by using the test of mou ear swelling induced by xylene and the weight of placing agar into subcutaneous of mou to induce granuloma The analgesic effects of TAA were obrved by using the test of mou twister induced by glacial acetic acid and the test of ache induced by hot were t up Results TAA have inhibitory effect to both of the inflammatory models and ache models TAA has some acute toxicity Conclusion TAA had anti-inflammatory and analgesic effects，andacute toxicity was appreciated
加密技术
