Characterization of the myeloid-derived suppressor cell subt regulated by NK cells in malignant林家宅37
lymphoma
红层>刘郎期刊名称： Oncoimmunology
作者： Sato, Yusuke,Shimizu, Kanako,Shinga, Jun,Hidaka, Michihiro,Kawano,
Fumio,Kakimi, Kazuhiro,Yamasaki, Satoru,Asakura, Miki,Fujii, Shin-ichiro
年份： 2015年橄榄油怎样食用
更上一层楼的上一句
退位减法怎么教期号： 第3期
四年级优秀作文关键词： IL-10; immunoregulation; malignant lymphoma; MDSC; NK cells
摘要：Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population with the ability to suppress immune respons and are currently classified into three distinct MDSC subts: monocytic, granulocytic and non-monocytic, and non-granulocytic MDSCs. Although NK cells provide an important
first-line defen against newly transformed cancer cells, it is unknown whether NK cells can regulate MDSC populations in the context of cancer. In this study, we initially found that the frequency of MDSCs in non-Hodgkin lymphoma (NHL) patients was incread and inverly correlated with that of NK cells, but not that
of T cells. To investigate the regulation of MDSC subts by NK cells, we ud an
EL4 murine lymphoma model and found the non-monocytic and non-granulocytic MDSC subt, i.e., Gr1+CD11b+Ly6GmedLy6Cmed MDSC, is incread after
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