Cost-effectiveness of using an extensively hydrolyzed cain formula supplemented with Lactobacillus rhamnosus GG in managing IgE-mediated cow's milk protein allergy in the UK 期刊名称： Current Medical Rearch and Opinion
作者： Julian F. Guest,Heenal Singh
年份： 2019年
期号： 第10期
关键词： Asthma;cost-effectiveness;cow’s milk protein allergy;extensively
hydrolyzed formula;Lactobacillus rhamnosus GG;UK
摘要：Objective: To estimate the cost-effectiveness of using an extensively
hydrolyzed cain formula (eHCF) plus the probiotic Lactobacillus rhamnosus GG
(eHCF plus LGG; Nutramigen* LGG®) compared to an eHCF alone as first-line dietary
management for Immunoglobulin E (IgE)-mediated cow's milk protein allergy
(CMPA) in the UK. Methods: Decision modelling was undertaken to estimate the
probability of IgE-mediated cow's milk allergic infants being symptom free (i.e. not
experiencing urticaria, eczema, asthma or rhinoconjunctivitis) and developing
tolerance to cow's milk by 5 years. The model also estimated the cost (at
2016/2017 prices) of healthcare resource u funded by the UK's National Health
Service (NHS) over 5 years after starting a formula, as well as the relative cost-
effectiveness of the two dietary formulae. Results:...
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