致癌物分类

更新时间:2023-07-29 22:13:03 阅读: 评论:0

致癌物分类
  IARC根据对人类和对实验动物致癌性资料,以及在实验系统和人类其他有关的资料(包括癌前病变、肿瘤病理学、遗传毒性、结构活性关系,代谢和动力学,理化参数及同类的生物因子)进行综合评价,将环境因子和类别、混合物及暴露环境与人类癌症的关系分为下列五类四组:
第一类:致癌
  组1,对人类是致癌物。对人类致癌性证据充分者属于本组。如吸烟和二手烟。
第二类:很可能致癌
  组心灵鸡汤经典语录励志2,对人类是很可能或可能致癌物。又分为两组,即组2A和组2B
  组2A,对人类很可能(probably)是致癌物,指对人类致癌性证据有限。对实验动物致癌性证据充分。如生产艺术玻璃、常用电吹风的理发师。
第三类:可能致癌
  组2B,对人类是可能(possible)致癌物,指对人类致癌性证据有限,对实验动物致癌性证据并不充分;或指对人类致癌性证据不足,对实验动物致癌性证据充分。
第四类:未知
  组3,现有的证据不能对人类致癌性进行分类。
第五类:很可能不致癌
  组4,对人类可能是非致癌物。
编辑本段致癌物五类明细表
  IARC专家组在20101月最新报告对834种环境因子和类别、混合物及暴露环境与人类癌症关系评价结果,
  其中组1100种,组1B68种,组2B246种,组3516种,组41种。
  IARC对化学物质引起人类癌症危险性评价,是目前公认的权威性资料。在要了解某种化
学物的致癌性时,应首先查阅IARC的资料(网址http1935116411/monoeval/crthgr01html)梦到黑蛇
  毒理学网 20101轮扁斫轮12
  Overall Evaluations of Carcinogenicity to Humans
  Group 1: Carcinogenic to humans (100)
  Agents and groups of agents
  4-Aminobiphenyl [92-67-1] (Vol. 1, Suppl. 7; 1987)
  Arnic [7440-38-2] and arnic compounds (Vol. 23, Suppl. 7; 1987) (NB:
  This evaluation applies to the group of compounds as a whole and not
  necessarily to all individual compounds within the group)
  Asbestos [1332-21-4] (Vol. 14, Suppl. 7; 1987)
  Azathioprine [446-86-6] (Vol. 26, Suppl. 7; 1987)
  Benzene [71-43-2] (Vol. 29, Suppl. 7; 1987)
  Benzidine [92-87-5] (Vol. 29, Suppl. 7; 1987)
  Benzo[a]pyrene [50-32-8] (Vol. 32, Suppl. 7, Vol. 92; in preparation)
  (NB: Overall evaluation upgraded from 2B to 1 bad on mechanistic and
  other relevant data)
  Beryllium [7440-41-7] and beryllium compounds (Vol. 58; 1993)
  N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornaphazine) [494-03-1] (Vol.
  4, Suppl. 7; 1987)
  Bis(chloromethyl)ether [542-88-1] and chloromethyl methyl ether [107-30-2]
  (technical-grade)
  (Vol. 4, Suppl. 7; 1987)
  1,4-Butanediol dimethanesulfonate (Busulphan; Myleran) [55-98-1] (Vol. 4,
  Suppl. 7; 1987)
  Cadmium [7440-43-9] and cadmium compounds (Vol. 58; 1993)
  Chlorambucil [305-03-3] (Vol. 26, Suppl. 7; 1987)
  1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU;
  Semustine) [13909-09-6] (Suppl. 7; 1987)
  Chromium[VI] (Vol. 49; 1990)
  Ciclosporin [79217-60-0] (Vol. 50; 1990)
  Cyclophosphamide [50-18-0] [6055-19-2] (Vol. 26, Suppl. 7; 1987)
  Diethylstilboestrol [56-53-1] (Vol. 21, Suppl. 7; 1987)
  Epstein-Barr virus (Vol. 70; 1997)
  Erionite [66733-21-9] (Vol. 42, Suppl. 7; 1987)
  Estrogen-progestogen menopausal therapy (combined) (Vol. 72, Vol. 91; in
  preparation)
异性推油  Estrogen-progestogen oral contraceptives (combined) (Vol. 72, Vol. 91; in
  preparation)
简单的画画教程
  (NB: There is also convincing evidence in humans that the agents confer
  a protective effect against cancer in the endometrium and ovary)
数学家的故事50字左右  Estrogens, nonsteroidal (Suppl. 7; 1987) (NB: This evaluation applies to
  the group of compounds as a whole and not necessarily to all individual
  compounds within the group)
  Estrogens, steroidal (Suppl. 7; 1987) (NB: This evaluation applies to
  有趣的灵魂the group of compounds as a whole and not necessarily to all individual
  compounds within the group)
  Estrogen therapy, postmenopausal (Vol. 72; 1999)
  Ethylene oxide [75-21-8] (Vol. 60; 1994) (NB: Overall evaluation upgraded
  from 2A to 1 with supporting evidence from other relevant data)
  Etoposide [33419-42-0] in combination with cisplatin and bleomycin (Vol.
  76; 2000)
  Formaldehyde [50-00-0] (Vol. 88; 2006)
  Gallium arnide [1303-00-0] (Vol. 86; 2006)
  [Gamma Radiation: e X- and Gamma (g)-Radiation]
  Helicobacter pylori (infection with) (Vol. 61; 1994)
  Hepatitis B virus (chronic infection with) (Vol. 59; 1994)
  Hepatitis C virus (chronic infection with) (Vol. 59; 1994)
  Human immunodeficiency virus type 1 (infection with) (Vol. 67; 1996)
  Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59
  and 66 (Vol. 64, Vol. 90; in preparation) (NB: The HPV types that have
  been classified as carcinogenic to humans can differ by an order of
  magnitude in risk for cervical cancer)
  Human T-cell lymphotropic virus type I (Vol. 67; 1996) 熨斗古镇
  Melphalan [148-82-3] (Vol. 9, Suppl. 7; 1987)
  8-Methoxypsoralen (Methoxsalen) [298-81-7] plus ultraviolet A radiation
  (Vol. 24, Suppl. 7; 1987)

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