西海情歌歌谱Identification, Characterization, Synthesis, and Strategy for Minimization of Potential Impurities Obrved in the Synthesis of Solithromycin组织意识
期刊名称: Organic Process Rearch & Development
入党推优发言稿年份: 2017年
中翅期号: 第9期
关键词: macrolide antibiotics;impurity;clarithromycin;solithromycin
给领导拜年短信摘要:Potential caus for the formation of synthetic impurities that are prent in solithromycin (1) during laboratory development are studied in the article. The impurities were monitored by HPLC, and their structures are identified on the basis of MS and NMR spectroscopy. In addition to the synthesis and characterization of the ven impurities, strategies for minimizing them to the level accepted by the International Conference on Harmonization (ICH) are also described.应届新课改
水蜜桃多肉
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