专利名称：ENGINEERED IMMUNE CELL TARGETING BCMA AND USE THEREOF
发明人：ZHANG, Hua，张华,SHI, Huan，石欢,SHEN,
Lianjun，沈连军,CAO, Wei，曹卫,LIU, Liping，刘丽萍申请号：CN2020/088836
申请日：20200506
园艺绿化公开号：WO2020/224606A1
董和
公开日：
务工合同
20201112送杯子的含义
关于友谊的手抄报
专利内容由知识产权出版社提供
摘要：The prent invention provides an engineered immune cell targeting BCMA and u thereof. In particular, the prent invention provides a CAR specifically targeting BCMA, the CAR comprising an antigen-binding domain which is an S-derived scFv and has an antibody heavy chain variable region as shown in SEQ ID NO: 9 and an antibody light chain variable region as shown in SEQ ID NO: 10. The prent invention also provides a CAR-T cell comprising the CAR, a double CAR and CAR T cell comprising the S-derived scFv, and related u thereof. Compared to CAR-T cells constructed using other scFvs, the constructed CAR-T cell of the prent invention has a better killing effect and tumor elimination capability.锅巴稀饭
申请人：GRACELL BIOTECHNOLOGIES (SHANGHAI) CO., LTD.，亘喜生物科技（上海）有限公司
地址：12th Floor, Building 1, 926 Yishan Road, Xuhui District Shanghai 200233 CN，中国上海市徐汇区宜山路926号1幢12层, Shanghai 200233 CN
生日快乐说说国籍：CN,CN
代理人：XU & PARTNERS, LLC.，上海一平知识产权代理有限公司更多信息请下载全文后查看
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