专利名称：IN VIVO ANTI-TUMOR ACTIVITY OF A
RECOMBINANT IL-7/HGF(BETA) HYBRID
CYTOKINE AND ASSOCIATED METHODS OF
USE
发明人：LAI, Laijun,GOLDSCHNEIDER, Irving
申请号：US2011/050199
申请日：20110901
公开号：WO2012/031115A2
公开日：
20120308
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摘要：The prent invention relates to a hybrid cytokine comprising IL-7 and HGF-β
and/or bioactive portions thereof, including a chimeric or fusion protein comprising an IL-7 polypeptide or bioactive portion thereof, and an HGF-β polypeptide or bioactive portion thereof, joined contiguously in a single polypeptide chain; and wherein the hybrid cytokine polypeptide inhibits the growth, proliferation, and/or metastasis of a cancer cell, in vivo.
申请人：UNIVERSITY OF CONNECTICUT,LAI, Laijun,GOLDSCHNEIDER, Irving
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代理人：MACDAVITT, Sean et al.
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