专利名称:CONJUGATED VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTI-TUMOR IMMUNE
REDIRECTORS
发明人:WANG, Joshua Weiyuan,INGAVAT,
我的家乡英语Nattha,MATSUI, Ken
申请号:EP19903832.4
申请日:20191226
公开号:EP3902527A1
公开日:
地震前的预兆
种子发芽实验
海口几线城市20211103
专利内容由知识产权出版社提供
摘要:Disclod is a new class of conjugated virus-like particles (VLPs), The conjugated VLPs bind a wide variety of tumors and compri epitopes recognized by a prior T cell immune respon already existing in a host. The epitopes are derived from pathogens or previous vaccinations (such as early childhood vaccines). This provokes the body's pre-existing cytotoxic immunity obtained through previous infection or previous childhood vaccination to be redirected to the tumor cells for tire elimination of cancer, and form long-term anti-tumor immunity. The described conjugated VLPs are uful for tailoring a broad range of tumors towards a respon from existing immunity circumventing the need to identify tumor antigens or generate tumor-specific immune respons, importantly, the compositions and methods described herein broadens opportunities for treatment for ail cancer types in subjects who previously had un-targetable cancers due to various technological and biological limitations of currently available immuno-therapeutic drugs.
申请人:VerImmune Inc.
无可比拟地址:1812 Ashland Ave Suite 100 Baltimore, MD 21205 US 国籍:US
兄弟情义
代理机构:FRKellypromoting
蘑菇炒肉更多信息请下载全文后查看