专利名称：BOTTLEBRUSH COPOLYMERS AND USES THEREOF
发明人：CHEN, Qixian,JOHNSON, Jeremiah, A.
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申请号：US2017/055145
申请日：20171004
公开号：WO2018/067702A1
公开日：
20180412
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摘要：Materials (., particles, hydrogels) that provide extended relea of one or more therapeutic agents are uful platforms for drug delivery. In part, the prent invention relates to new triblock (ABC) bottlebrush copolymers which can be ud in the
formulation of particles and hydrogels for the extended relea of therapeutic agents. In certain embodiments, the triblock bottlebrush copolymers, particles, and hydrogels described herein are thermally-responsive and gel at physiological temperature (., upon administration to a subject), providing injectable and/or implantable gels which can be ud for extended relea drug delivery. The prent invention also provides methods for extended relea drug delivery, and methods of treating and/or preventing a dia or conditions in a subject, using the inventive copolymers, particles, and hydrogels. In addition, the prent invention provides methods of preparing the triblock bottlebrush copolymers described herein.
申请人：MASSACHUSETTS INSTITUTE OF TECHNOLOGY,VOHIDOV, Farrukh
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地址：77 Massachutts Avenue Cambridge, MA 02139 US,120 Palmer Street Arlington, MA 02474 US
国籍：US,US初中物理课本
代理人：HAMZIK, Philip, J.
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