专利名称：SMAD BINDING ELEMENTS AND USES THEREOF
发明人：JONK, Luigi, J., C.,ITOH, Susumo,HELDIN, Carl-Henrik,TEN DIJKE, Peter,KRUIJER,
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三国演义简介申请号：US1999004740
精妙绝伦申请日：19990303
公开号：WO99/045113P1
飞young宽带公开日：
19990910
引人注目反义词>防水怎么施工专利内容由知识产权出版社提供
摘要：The invention provides isolated nucleic acids including one or more Smad binding elements (SBEs) and Smad proteins and fragments thereof which bind to Smad binding elements. The invention also provides TGFβ respon elements which confer TGFβ superfamily responsiveness to genes which have such elements in transcriptional control regions. Also provided are methods for using the Smad binding elements in methods of screening for compounds which bind the Smad binding element and in methods for modulating the binding of Smad proteins to Smad binding elements, e.g. to modulate TGFβ signal transduction. Further, the identification of a mammalian Smad binding quence permits identification of the SBE binding determinants of Smad proteins.
申请人：LUDWIG INSTITUTE FOR CANCER RESEARCH,UNIVERSITY OF GRONINGEN 地址：US,NL
主持人台词大全国籍：US,NL
五花肉金针菇代理机构：VAN AMSTERDAM, John, R.更多信息请下载全文后查看
