黑洁明小说专利名称:PROCESS FOR PREPARING DIPEPTIDYL IV INHIBITORS AND INTERMEDIATES
THEREFOR
电脑锁屏怎么设置发明人:POLITINO, MICHAEL,CADIN, MATTHEW M.,SKONEZNY, PAUL M.,CHEN, JASON G.
生产厂长岗位职责申请号:US2005012615host
申请日:20050413
公开号:WO2005106011A3广告设计图
菠萝的英语公开日:
20061026怎么做煲仔饭
专利内容由知识产权出版社提供
摘要:A process for production of cyclopropyl-fud pyrrolidine-bad inhibitors of dipeptidyl peptida IV is provided which employs a BOC-protected amine of the structure (3) prepared by subjecting an acid of the structure (1) to reduce amination by treating the acid with ammonium formate, nicotinamide adenine dinucleotide, dithiothreitol and partially purified phenylalanine dehydrogena/formate dehydrogena enzyme concentrate (PDH/FDH) and without isolating treating the resulting amine of the structure (2) with di-tert-butyl dicarbonate to form the BOC-protected amine.
仰卧起坐申请人:BRISTOL-MYERS SQUIBB COMPANY,POLITINO, MICHAEL,CADIN, MATTHEW M.,SKONEZNY, PAUL M.,CHEN, JASON G.
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