专利名称：I-Sce I induced gene replacement and gene conversion in embryonic stem cells太早吉他谱
发明人：Frederic Jaisr,Michel Cohen-
Tannoudji,Sylvie Robine,Andre市场调研分析报告
Choulika,Daniel Louvard,Charles Babinet
申请号：US09116834
申请日：19980717
公开号：US06566579B1
公开日：属羊是什么命
20030520大学生就业形势
六年级下册语文书专利内容由知识产权出版社提供
摘要：The invention relates to methods of introducing a heterologous DNA quence into a mou embryonic stem cell wherein the DNA quence is inrted by homologous recombination into a villin gene/I-SceI hybrid by creating a double strand break with I-SceI meganuclea. Subquently, the mou embryonic stem cells can be ud to generate a transgenic mou comprising the heterologous DNA quence. Additionally, the methods can be ud for gene replacement in ovo where a mou oocyte containing a villin gene/I-SceI hybrid within its genome exists or is first generated. More generally, the methods can be ud for the targeted inrtion of a heterologous DNA quence into any cell containing a villin gene/I-SceI hybrid quence within its genome.
美丽心灵电影>小学一年级古诗词
申请人：INSTITUT PASTEUR,INSTITUT CURIE,CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE
自制鲫鱼窝料代理机构：Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
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