核苷酸结合结构域英语

更新时间:2023-07-15 05:49:51 阅读: 评论:0

核苷酸结合结构域英语
    Nucleotide binding domains (NBDs) reprent a group of protein domains that are responsible for binding and hydrolyzing nucleotides such as ATP (adenosine triphosphate) and GTP (guanine triphosphate). The domains play important roles in a wide range of cellular process including signaling, transport and energy metabolism. 惠斯顿电桥
    The structure of NBDs consists of a highly conrved central nucleotide-binding site surrounded by variable regions. The nucleotide-binding site is characterized by a t of conrved amino acid residues that form specific interactions with the nucleotide substrate. In addition, NBDs also have specific motifs like the Walker A and B motifs, which are important for ATP binding and hydrolysis.
防疫不力
    NBDs are found in a variety of proteins and can be divided into two families: the P-loop NTPa family, which includes proteins such as Ras, and the ABC (ATP-binding castte) transporter family, which are involved in transport process. The ABC transporters, in particular, contain two NBDs that form a dimeric structure and are responsible for ATP hydr
olysis that drives transport of substrates across cellular membranes. 米兰理工大学
授衔仪式
mp3在线试听    Mutations in NBDs have been linked to a variety of dias including cystic fibrosis, which is caud by mutations in the ABC transporter CFTR (cystic fibrosis transmembrane conductance regulator), and cardiovascular dia, which is associated with the ATP-binding protein, Abca1. 漳州南山寺
蓟县溶洞
    In summary, NBDs are important domains in proteins that are involved in a variety of cellular process. They have a highly conrved nucleotide-binding site and specific motifs that are esntial for their function. Mutations in NBDs have been linked to veral dias, highlighting their importance in maintaining cellular homeostasis.护发素推荐

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