专利名称：POLYPEPTIDES DERIVED FROM AMYLOID PRECURSOR PEPTIDE (APP) AND THEIR USES 发明人：MILEUSNIC, Radmila,ROSE, Steven, Peter,
Rusll
申请号：GB2002001769
申请日：20020417
全民创业
公开号：WO02/083729P1
公开日：
制义
纸房子20021024王鲁豫
专利内容由知识产权出版社提供
摘要：The invention provides a compound having formula X1-Arg-Xaa-Arg-X2 in which X1 and X2 are up to 30 amino acid residues and Xaa is an amino acid residue. A preferred compound is the tripeptide Arg-Glu-Arg which corresponds to amino acid residues 328 to 330 of human amyloid precursor protein. The invention further provides a derivative of a polypeptide having the formula: X1-Arg-Xaa-Arg-X2 wherein X1 and X2, which may be the same or different, each reprents from zero to 30 natural or synthetic amino acid residues or derivatives thereof and Xaa reprents a natural or synthetic amino acid residue or derivative thereof, at least one functional group of at least one said amino acid residue or derivative thereof being protected by a protective group. The compounds of the invention are believed to be uful in the treatment of Alzheimer's dia and as cognitive enhancers.
申请人：MILEUSNIC, Radmila,ROSE, Steven, Peter, Rusll摩擦起电的原理>长沙会战
极度伤感的句子地址：Walton Hall Milton Keynes MK7 6BT GB,c/o Department of Biological Sciences The Open University Milton Keynes MK7 6AA GB,c/o Department of Biological Sciences The Open University
Milton Keynes MK7 6AA GB
国籍：GB,GB,GB
代理机构：ACKROYD, Robert 更多信息请下载全文后查看
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