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牛排的制作方法>十大古文名篇Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer
南瓜小米粥的功效丰富的英语怎么说analysis所开头的成语
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期刊名称： OncoImmunology
作者： Baihui Li,Bailu Zhang,Xuezhou Wang,Ziqing Zeng,Lili Yang
煤球精灵年份： 2020年
期号： 第1期
关键词： Siglec-15;prognosis;cancer Immunity;pathway;multi-omics
Bioinformatics
摘要：Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) is considered a novel anti-tumor target comparable to programmed cell death 1 ligand 1(PD-L1). However, little is known about Siglec-1
5. Our study aims to understand its expression signature, prognosis value, immune infiltration pattern, and biological function using multi-omic bioinformatics from public databas and verify them in lung cancer patients. Integrated analysis of The Cancer Genome Atlas and Genotype-Tissue Expression portals showed Siglec-15 was overexpresd across cancers. Genetic and epigenetic alteration analysis was performed using cBioportal and UALCAN, showed Siglec-15 was regulated at the genetic and epigenetic levels. Survival estimated using Kaplan–Meier plotter indicated high Siglec-15 expression correlated with favorable or
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