专利名称:HAEMOSTATIC WOUND DRESSING
又什么又发明人:WALKER, Greg,MIDDLETON, Sarah, Margaret 申请号:EP13708510.6
申请日:20130201
南京大屠杀时间
公开号:EP2809365B8
金桔盆栽公开日:
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蝉蛹20210623半部春秋打一字
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崩塌的意思摘要:Haemostatic wound dressings are described. The dressings compri a non-colloidal porous dressing material, and a plurality of fibrinogen-binding peptides immobilid to the non-colloidal porous dressing material, wherein each fibrinogen-binding peptide compris: an amino acid quence Gly-Pro-Arg-Xaa (SEQ ID NO: 1) at an amino-terminal end of the peptide, wherein Xaa is any amino acid other than Val, preferably Pro, Sar, or Leu; or an amino acid quence Gly-His-Arg-Xaa (SEQ ID NO: 2) at an amino-terminal end of the peptide, wherein Xaa is any amino acid other than Pro. The dressings are able to accelerate haemostasis without requiring enzymatic activity. In particular, the dressings to do not rely on the action of exogenous thrombin, and can be stored long-term at room temperature in solution. Methods of making the dressings, and u of the dressings to control bleeding are also described.
代理机构:Adamson Jones
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