SPLIT LUCIFERASE, AND HIGHLY SENSITIVE VITAMIN D R

更新时间:2023-06-27 10:00:25 阅读: 评论:0

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专利名称:SPLIT LUCIFERASE, AND HIGHLY SENSITIVE VITAMIN D RECEPTOR LIGAND DETECTION
METHOD USING SAME只要宝宝不要爹
发明人:SAKAKI, Toshiyuki,NISHIKAWA, Miyu,MANO, Hiroki
不慌不忙类似的词语申请号:EP18873933
申请日:20181031
形容女生
公开号:EP3705574A4缺点是什么意思
公开日:
总是的英文
20210929
专利内容由知识产权出版社提供
摘要:The prent invention pertains to any fusion protein in (1) to (3): (1) a fusion protein containing, in no particular order, the lucifera N-terminal domain (LucN), at least one vitamin D-binding domain of a vitamin D receptor (VDR), and the lucifera C-terminal domain (LucC), and able to additionally include, in no particular order, an
LX1X2LL quence and/or a linker quence; (2) a fusion protein containing, in no particular order, LucN or LucC, and an LX1X2LL quence, and able to additionally include, in no particular order, a linker quence; and (3) a fusion protein containing, in no particular order, at least one vitamin D-binding domain of a VDR, and LucC or LucN, and able to additionally include, in no particular order, a linker quence. The prent invention also pertains to a method for screening, using the fusion protein, for substances which demonstrate the ability to bind to VDRs. The prent invention provides a bionsor in which the luminescence increas when an agonist binds thereto, and provides a method for easily screening for substances which bind strongly to vitamin D receptors (V
含有月亮的诗句
DRs).
洗手日申请人:Public University Corporation Toyama Prefectural University 更多信息请下载全文后查看

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