专利名称:MONOCLONAL ANTIBODIES AGAINST THE ALPHA PDGF RECEPTOR AND USES
THEREOF
美女泳装图发明人:LaROCHELLE, William, J.,PIERCE,
Jacalyn,JENSEN, Roy, A.,AARONSON, Stuart,
A.
申请号:US1994007006
申请日:19940624
奢侈品牌有哪些公开号:WO95/000659P1
公开日:添加书签
清明这首诗
19950105
气郁
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摘要:Potent neutralizing monoclonal antibodies to the human α PDGF receptor (αPDGFR) and fragments thereof are described. The monoclonal antibodies specifically bind to an epitope on α PDGFR, inhibit PDGF binding with PDGF receptor, antagonize PDGF, and do not bind β PDGF receptor. A hybridoma cell line producing such a monoclonal antibody, methods of in vivo imaging of a pathological condition and methods of inhibiting the growth of a neoplasia expressing α PDGFR, which u the monoclonal antibodies are also described. In vitro assays for detecting the prence of αPDGFR and for evaluating the binding affinity of a test compound are also described.
申请人:THE UNITED STATES OF AMERICA, reprented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
一年级手抄报模板地址:US
国籍:US
属水的颜色代理机构:BENT, Stephen, A.更多信息请下载全文后查看